Due to upcoming patent expirations for four high-profile drugs, the
global Parkinson’s Disease (PD) market is expected to decline from $3.4 billion
in 2012 to $2.9 billion by 2019, at a negative Compound Annual Growth Rate
(CAGR) of 2.3%.
The latest report states that PD drugs, such as Azilect (rasagiline
mesylate), Stalevo (levodopa, carbidopa, entacapone) and Comtan (entacapone),
will lose their patents by the end of the forecast period. Generic alternatives
for these treatments have already been approved, which will result in further
market competition.
Additionally, the loss of patent for Mirapex (pramipexole
dihydrochloride) and Exelon (rivastigmine tartrate) in 2010 and 2012 will
continue to halt future PD market growth.
Analyst of this report says: “In the most likely scenario, late-stage
pipeline drugs, including Rytary, safinamide and pimavanserin, are expected to
be approved and launched in the market within the forecast period. However, this
won’t be significant enough to diminish the impact of generic erosion.”
Furthermore, with the majority of existing PD drugs focusing on
symptomatic relief, a disease-modifying treatment remains an urgent unmet need
in the PD market. The current pipeline consists of 21% neuroprotective targets,
while 87% are currently in discovery and preclinical development. The remaining
molecules are distributed in Phase I and Phase II.
“These targets represent innovation in the pipeline and could become
effective disease-modifying treatments in the future. However, the development
of such medication faces several challenges, including the absence of
neuroprotective candidates in the late pipeline and the need for a reliable
biomarker that can accelerate such development,” the analyst concludes.
This report provides in-depth analysis of the drugs available for the
treatment of Parkinson’s Disease, covering their safety, efficacy, treatment
patterns, and strengths/weaknesses, as well as a heat map comparing drugs in
terms of safety and efficacy. It gives multi-scenario market forecast data to
2019, taking into account the introduction of new drugs, the expiration of key
patents, and changes in disease epidemiology across the US, Canada, France,
Germany, Italy, Spain, the UK and Japan.
For more information please
visit: http://www.marketresearchreports.com/gbi-research/parkinsons-disease-therapeutics-market-2019-pipeline-shows-shift-towards-long-term
Browse other market research reports in
diseases at http://www.marketresearchreports.com/diseases
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