Big Pharma Drives Innovation in Pain Therapy Development, Despite
Declining Patent Applications
Patent applications for novel pain therapeutics declined steadily in
number from 4,970 in 2008 to 3,492 in 2012, an average annual decrease of 8%,
as limited understanding of pain pathophysiology continues to hinder drug
development in this arena, according to new report.
The company’s latest report states that patent applications for pain
treatments between 2008 and 2012 were dominated by Big Pharma, including
Sanofi, Novartis and Merck & Co. (Merck), which submitted 169, 162 and 142
applications, respectively.
However, according to Publisher, the global pain treatment market is
dominated by opioids and steroidal anti-inflammatory drugs, with no novel
products currently able to challenge these products’ efficacy in treating
moderate to severe acute pain.
Furthermore, despite the significant unmet needs for more effective
therapies in other pain subtypes, such as chronic and neuropathic pain, due to
their rising prevalence, the factors underpinning these subtypes are complex
and poorly understood.
However, this limited knowledge is being countered by technological
advances and significant research efforts, with new insights translating into
an expanding pool of novel therapeutic targets.
Publisher states that the overall pain therapy pipeline is exceptionally
large and moderately diverse, with a number of molecules boasting different
mechanisms of action to those seen in the current market landscape. This offers
a high probability of producing strong market entrants in the near future.
Indeed, among the 111 first-in-class pipeline products available for
strategic consolidations, some have shown promising Preclinical evidence and
significant potential to become game-changing treatments, representing
high-reward investments.
Publisher believes that such innovation in the pain therapeutics field
is being driven primarily by Big Pharma, due to the large number of patent
grants awarded to these companies for their treatments between 2008 and 2012.
Merck boasted the highest number of patent grants during this period,
with 59, while Boehringer Ingelheim and Allergan achieved 35 and 34,
respectively, and Sanofi and Novartis both achieved 30.
Frontier Pharma: Pain - Identifying and Commercializing First-in-Class
Innovation report provides a comprehensive review of the pipeline for
first-in-class pain therapies, analyzed on the basis of stage of development,
molecule type and molecular target. The report also assesses the licensing and
co-development deal landscape for pain therapies and the benchmarking of deals
involving first-in-class versus non-first-in-class products.
For
further information on this report, please visit- http://mrr.cm/4x7
Find all Diseases Reports at: http://www.marketresearchreports.com/diseases
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