Report forecast the global opioid-induced
constipation market to grow at a CAGR of 30.18% over the period 2014-2019.
Opioids are administered to the patients with acute
and non-cancer chronic pain. They have several adverse gastrointestinal
effects, one of which is opioid-induced constipation. The opioid analgesics
produce analgesia by the activation of the mu receptors found in the CNS and
PNS. These drugs affect the motility, tone, and contractility of the bowel
functions, which results in the delay in the transit of fecal contents. The
opioids also cause a reduction in the secretion of digestive enzymes and also
cause partial gastroparesis. Some of the common symptoms of opioid-induced
constipation are hard and dry stools, painful defecation, bloating, distention
and bulged abdomen, feeling lethargic, and loss of appetite. Opioid-induced
constipation can be managed by changing lifestyle along with the use of
targeted therapies and other OTC and off-label drugs.
This report covers the present scenario and the
growth prospects of the global opioid-induced constipation market for
2015-2019. To calculate the market size, the report considers revenue generated
from sales of various drugs used in the treatment of opioid-induced constipation,
which includes branded drugs, off-label products, and OTC drugs.
On the basis of the mechanism of action of drugs,
the market is grouped into the following categories:
- Peripherally Acting Mu-opioid Receptor Antagonist
- Locally Acting Chloride Channel Activator
- Others
On the basis of the route of administration of
drugs, the market is grouped into the following categories:
- Oral
- Parenteral
On the basis of the dosage form of drugs, the
market is grouped into the following categories:
- Solid
- Liquid
According to the report, the low levels of
awareness about opioid-induced constipation among patients and the medical
fraternity have resulted in the usage of off-label and OTC medications as the
treatment options. However, these drugs are only partially successful in
treating this condition. The entry of peripherally acting mu-opioid receptor
antagonists such as Movantik/Moventig has driven the market significantly. The
drug targets the underlying cause of opioid-induced constipation without
affecting the analgesic action of the opioid drugs. Therefore, this is
increasingly becoming the preferred treatment option for opioid-induced
constipation.
Further, the report states that the availability of
OTC and off-label drugs restricts the market growth.
Global Opioid-induced Constipation Market
2015-2019, has been prepared based on an in-depth market analysis with
inputs from industry experts. The report covers the market landscape and its
growth prospects in the coming years. The report also includes a discussion of
the key vendors operating in this market.
key players in the Global Opioid-Induced
Constipation Market: AstraZeneca, Takeda Pharmaceutical and Valeant
Pharmaceuticals International
Other Prominent Vendors in the market are: Abbott,
Bayer, Boehringer Ingelheim, C.B. Fleet, Cosmo Pharmaceuticals, Daewoong,
Daiichi Sankyo, GlaxoSmithKline, Ironwood Pharmaceuticals, Johnson &
Johnson, Merck, Mundipharma, Nektar Therapeutics, Pfizer, Progenics
Pharmaceuticals, Shionogi, SLA Pharma, Sucampo, Synergy Pharmaceuticals and
Theravance
Key Regions
- Americas
- APAC
- EMEA
Market Driver
- Unmet Medical Needs
- For a full, detailed list, view our report
Market Challenge
- Availability of OTC and Off-label Drugs
- For a full, detailed list, view our report
Market Trend
- Shift to Targeted Therapy
- For a full, detailed list, view our report
Key Questions Answered in this Report
- What will the market size be in 2019 and what will the growth rate be?
- What are the key market trends?
- What is driving this market?
- What are the challenges to market growth?
- Who are the key vendors in this market space?
- What are the market opportunities and threats faced by the key vendors?
- What are the strengths and weaknesses of the key vendors?
Spanning over 69 pages and 23 Exhibits
“Global
Opioid-Induced Constipation Market 2015-2019” report covers Executive
Summary, List of Abbreviations, Scope of the Report, Market Research
Methodology, Introduction, Product Profiles, Disease Overview, Pipeline
Portfolio, Market Landscape, Market Segmentation by Mechanism of Action, Market
Segmentation by Route of Administration, Market Segmentation by Dosage Form,
Geographical Segmentation, Buying Criteria, Market Growth Drivers, Drivers and
their Impact, Market Challenges, Impact of Drivers and Challenges, Market
Trends, Trends and their I.act, Vendor Landscape, Key Vendor Analysis.
For
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