Histone Deacetylase 2 (Transcriptional Regulator
Homolog RPD3 or YY1-Associated Factor 1 or EC 3.5.1.98) Histone deacetylase 2
is an enzyme encoded by the HDAC2 gene. It plays an important role in
transcriptional regulation, cell cycle progression and developmental events.
Histone deacetylases act via the formation of large multiprotein complexes. It
forms transcriptional repressor complexes by associating with MAD, SIN3, YY1
and N-COR. It interacts in the late S-phase of DNA-replication with DNMT1 in
the other transcriptional repressor complex composed of DNMT1, DMAP1, PCNA, and
CAF1. It deacetylates TSHZ3 and regulates its transcriptional repressor
activity.
Histone Deacetylase 2 (Transcriptional Regulator
Homolog RPD3 or YY1-Associated Factor 1 or EC 3.5.1.98) pipeline Target
constitutes close to 18 molecules. Out of which approximately 17 molecules are
developed by Companies and remaining by the Universities/Institutes. The
molecules developed by Companies in Phase III, Phase II, Phase I, Preclinical
and Discovery stages are 2, 5, 1, 6 and 3 respectively. Similarly, the
Universities portfolio in Discovery stages comprises 1 molecules, respectively.
The report Histone Deacetylase 2 – Pipeline Review,
H1 2016, outlays comprehensive information on the Histone Deacetylase 2
(Transcriptional Regulator Homolog RPD3 or YY1-Associated Factor 1 or EC
3.5.1.98) targeted therapeutics, complete with analysis by indications, stage
of development, mechanism of action (MoA), route of administration (RoA) and
molecule type. It also reviews key players involved in Histone Deacetylase 2
(Transcriptional Regulator Homolog RPD3 or YY1-Associated Factor 1 or EC
3.5.1.98) targeted therapeutics development, features dormant and discontinued
projects and latest news and press releases.
The report is built using data and information
sourced from Global Markets Direct’s proprietary databases, company/university
websites, clinical trial registries, conferences, SEC filings, investor
presentations and featured press releases from company/university sites and
industry-specific third party sources.
Scope
- The report provides a snapshot of the global therapeutic landscape for Histone Deacetylase 2 (Transcriptional Regulator Homolog RPD3 or YY1-Associated Factor 1 or EC 3.5.1.98)
- The report reviews Histone Deacetylase 2 (Transcriptional Regulator Homolog RPD3 or YY1-Associated Factor 1 or EC 3.5.1.98) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in Histone Deacetylase 2 (Transcriptional Regulator Homolog RPD3 or YY1-Associated Factor 1 or EC 3.5.1.98) targeted therapeutics and enlists all their major and minor projects
- The report assesses Histone Deacetylase 2 (Transcriptional Regulator Homolog RPD3 or YY1-Associated Factor 1 or EC 3.5.1.98) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
- The report summarizes all the dormant and discontinued pipeline projects
- The report reviews latest news and deals related to Histone Deacetylase 2 (Transcriptional Regulator Homolog RPD3 or YY1-Associated Factor 1 or EC 3.5.1.98) targeted therapeutics
Reasons to buy
- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Identify and understand the targeted therapy areas and indications for Histone Deacetylase 2 (Transcriptional Regulator Homolog RPD3 or YY1-Associated Factor 1 or EC 3.5.1.98)
- Identify the use of drugs for target identification and drug repurposing
- Identify potential new clients or partners in the target demographic
- Develop strategic initiatives by understanding the focus areas of leading companies
- Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
- Devise corrective measures for pipeline projects by understanding Histone Deacetylase 2 (Transcriptional Regulator Homolog RPD3 or YY1-Associated Factor 1 or EC 3.5.1.98) development landscape
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
For
more information Visit at: http://mrr.cm/JDS
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Agammaglobulinemia Tyrosine Kinase or EC 2.7.10.2) - Pipeline Review, H1 2016 -
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Poly (ADP-Ribose) Polymerase 1
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