Report forecast the global breast cancer monoclonal
antibodies (mAbs) market to post a revenue of 13.7 billion by 2020.
Breast cancer is characterized by the malignancy of cells in
the tissues of the breast. HER-2 breast cancer is the most common type of
breast cancer. The HER-2 protein, present on the surface of normal breast
cells, affects the growth of the malignant cells. The uncontrolled synthesis of
this protein stimulates the growth and division of malignant cells. Antibodies
are the proteins produced by B-cells (in the bone marrow) in the immune system.
These proteins attach themselves to antigens, which act as markers, and are
then destroyed by phagocytes. B-cells produce different antibodies, which
attach themselves to different sites of an antigen. mAbs are monospecific, as
they are the clones of a single parent cell.
The report covers the present scenario and the growth
prospects of the global breast cancer monoclonal antibodies (mAbs) market for
2016-2020. To calculate the market size, the report considers the revenue
generated from the sale of branded mAbs and biosimilars used to treat breast
cancer.
The market is divided into the following segments based
on geography:
- Americas
- APAC
- EMEA
According to the report, exposure to risk factors will be a
key driver for market growth. Exposure to risk factors for breast cancer and
the decrease in practices that reduce this risk are expected to increase the
incidence of breast cancer. The disease is associated with modifiable risk
factors such as physical inactivity, alcohol consumption, obesity, and weight
gain. For instance, the use of hormonal therapy after menopause and the use of
contraceptives are potential risks for developing breast cancer. Oral contraceptives
and postmenopausal estrogen-progestogen hormone replacement therapy increase
the risk of the developing the disease because they contain synthetic sex
hormones. Overweight postmenopausal women have elevated estrogen levels because
they have more estrogen-producing fatty tissue. These levels increase the
likelihood of developing the disease. Physical activity helps lower estrogen
levels, and thus negates the risk factors. Breastfeeding is also known to
protect women against breast cancer.
Further, the report states that the number of patients
available for clinical studies is less, making it difficult to generate
significant comparative data. This is a major challenge in conducting clinical
studies and for the market. The participation of sites across multiple
geographies is required, but only very few patients are enrolled at each site.
This may lead to delays in the recruitment process, which can add to the cost
and uncertainty of the program. Pharmaceutical companies developing mAbs
conduct clinical trials on a limited patient population. This requires efforts
to mitigate the higher risk of uncertainty associated with the use of these
drugs and accelerates approval procedures. The US FDA mandates manufacturers to
satisfy Risk Evaluation and Mitigation Strategy (REMS) programs that include
elements to ensure safe use before and after approval. The assessment of safety
labels during clinical trials becomes difficult because of the limited
availability of premarket data for the evaluation of mAbs and the smaller
patient population.
Global Breast Cancer Monoclonal Antibodies (mAbs) Market
2016-2020, has been prepared based on an in-depth market analysis with
inputs from industry experts. The report covers the market landscape and its
growth prospects over the coming years. The report also includes a discussion
of the key vendors operating in this market.
key players in the global breast cancer monoclonal
antibodies (mAbs) market: Roche, Amgen, and Mylan.
Other Prominent Vendors in the market are: Actavis, Array
BioPharma, AstraZeneca, Biocad, Boehringer Ingelheim, Bristol-Myers Squibb,
Celldex Therapeutics, Celltrion, Chugai Pharmaceutical, Daiichi Sankyo, DARA
Biosciences, Eddingpharm, Eisai, Galena Biopharma, GlaxoSmithKline, Halozyme
Therapeutics, Hospira, ImmunoGen, Immunomedics, MacroGenics, Merck, Novartis,
Oncothyreon, Pfizer, ProStrakan, Puma Biotechnology, Seattle Genetics, Sun
Pharmaceutical Industriesf, Synta Pharmaceuticals, and Teva Pharmaceuticals.
Market driver
- Reimbursement benefits for breast cancer mAbs
- For a full, detailed list, view our report
Market challenge
- Absence of adequate diagnosis and screening procedures for early detection
- For a full, detailed list, view our report
Market trend
- Emergence of targeted and combination therapies for breast cancer
- For a full, detailed list, view our report
Key questions answered in this report
- What will the market size be in 2020 and what will the growth rate be?
- What are the key market trends?
- What is driving this market?
- What are the challenges to market growth?
- Who are the key vendors in this market space?
- What are the market opportunities and threats faced by the key vendors?
- What are the strengths and weaknesses of the key vendors?
Spanning over 88 pages and 56 Exhibit “Global
Breast Cancer Monoclonal Antibodies Market 2016 - 2020” report covers Executive
summary, Scope of the report, Market research methodology, Introduction, Market
landscape, Breast cancer: Overview, Pipeline portfolio, Market segmentation by
type of mAbs, Market segmentation by end-user, Geographical segmentation,
Market drivers, Impact of drivers, Market challenges, Impact of drivers and
challenges, Market trends, Vendor landscape, Appendix.
For
more information Visit at: http://mrr.cm/3qJ
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