Dupuytren Contracture - Pipeline Review, H2
2017, provides an overview of the Dupuytren Contracture (Musculoskeletal
Disorders) pipeline landscape.
Dupuytren contracture is a hand deformity
that usually develops slowly, over decades. Dupuytren contracture affects the
connective tissue under the skin of the palm. It is a localized formation of
scar tissue beneath the skin of the palm of the hand. The scarring accumulates
in a tissue that normally covers the tendons that pull the fingers to grip. As
Dupuytren contracture progresses, more of the fascia becomes thickened and
shortened. Dimpling and puckering of the skin over the area eventually occurs.
Dupuytren contracture varies in its rate of progression from minor skin
puckering for many years to rapid contracture (fixed flexed position) of
fingers. Dupuytren contracture can lead to an inability to fully extend the
affected finger from the flexed position.
This can result in a loss of normal
grasping. Dupuytren contracture is seldom associated with much, if any, pain
unless the affected fingers are inadvertently forcefully hyperextended.
Dupuytren contracture is a fibroproliferative disorder. It involves the tissue
beneath the palm of the hand that leads to finger contracture and may result in
significant deformity and disability. Factors contributing to the disease
include ethnicity, genetic predisposition, sex and age. Risk factors
(environmental) include alcohol consumption, smoking, trauma, epilepsy and diabetes.
Dupuytren contracture is usually treated by an operation to straighten the
fingers followed by therapy if the angle that the fingers are bent at is large
enough.
Surgical treatment requires extensive
postoperative therapy and there are chances that symptoms often re-occur. The
molecular pathophysiology of Dupuytren contracture is complex. Extensive
exploration of the molecular basis of Dupuytren contracture has led to the
development of new treatment modalities such as by Clostridium histolyticum collagenase
injection. There still remains a long way in the development of more promising
therapies for Dupuytren contracture.
Report
Highlights
Dupuytren Contracture - Pipeline Review, H2
2017, provides comprehensive information on the therapeutics under development
for Dupuytren Contracture (Musculoskeletal Disorders), complete with analysis
by stage of development, drug target, mechanism of action (MoA), route of
administration (RoA) and molecule type. The guide covers the descriptive
pharmacological action of the therapeutics, its complete research and
development history and latest news and press releases.
The Dupuytren Contracture (Musculoskeletal
Disorders) pipeline guide also reviews of key players involved in therapeutic
development for Dupuytren Contracture and features dormant and discontinued
projects. The guide covers therapeutics under Development by Companies
/Universities /Institutes, the molecules developed by Companies in Phase II,
Preclinical and Discovery stages are 2, 1 and 1 respectively. Similarly, the
Universities portfolio in Phase II stages comprises 1 molecules, respectively.
Dupuytren Contracture (Musculoskeletal
Disorders) pipeline guide helps in identifying and tracking emerging players in
the market and their portfolios, enhances decision making capabilities and
helps to create effective counter strategies to gain competitive advantage. The
guide is built using data and information sourced from Publisher’s proprietary
databases, company/university websites, clinical trial registries, conferences,
SEC filings, investor presentations and featured press releases from
company/university sites and industry-specific third party sources.
Additionally, various dynamic tracking processes ensure that the most recent
developments are captured on a real time basis.
Scope
- The pipeline guide provides a snapshot of the global therapeutic landscape of Dupuytren Contracture (Musculoskeletal Disorders).
- The pipeline guide reviews pipeline therapeutics for Dupuytren Contracture (Musculoskeletal Disorders) by companies and universities/research institutes based on information derived from company and industry-specific sources.
- The pipeline guide covers pipeline products based on several stages of development ranging from pre-registration till discovery and undisclosed stages.
- The pipeline guide features descriptive drug profiles for the pipeline products which comprise, product description, descriptive licensing and collaboration details, R&D brief, MoA & other developmental activities.
- The pipeline guide reviews key companies involved in Dupuytren Contracture (Musculoskeletal Disorders) therapeutics and enlists all their major and minor projects.
- The pipeline guide evaluates Dupuytren Contracture (Musculoskeletal Disorders) therapeutics based on mechanism of action (MoA), drug target, route of administration (RoA) and molecule type.
- The pipeline guide encapsulates all the dormant and discontinued pipeline projects.
- The pipeline guide reviews latest news related to pipeline therapeutics for Dupuytren Contracture (Musculoskeletal Disorders)
Reasons
to buy
- Procure strategically important competitor information, analysis, and insights to formulate effective R&D strategies.
- Recognize emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage.
- Find and recognize significant and varied types of therapeutics under development for Dupuytren Contracture (Musculoskeletal Disorders).
- Classify potential new clients or partners in the target demographic.
- Develop tactical initiatives by understanding the focus areas of leading companies.
- Plan mergers and acquisitions meritoriously by identifying key players and it’s most promising pipeline therapeutics.
- Formulate corrective measures for pipeline projects by understanding Dupuytren Contracture (Musculoskeletal Disorders) pipeline depth and focus of Indication therapeutics.
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope.
- Adjust the therapeutic portfolio by recognizing discontinued projects and understand from the know-how what drove them from pipeline.
Spanning over 31 pages “Dupuytren
Contracture - Pipeline Review, H2 2017” report covers Introduction,
Report Coverage, Dupuytren Contracture - Overview, Dupuytren Contracture -
Therapeutics Development, Dupuytren Contracture - Therapeutics Assessment,
Dupuytren Contracture - Companies Involved in Therapeutics Development,
Dupuytren Contracture - Drug Profiles, Product Description, Dupuytren Contracture
- Dormant Projects, Appendix. This report Covered Companies - MediWound Ltd,
Pacira Pharmaceuticals. Inc
Please visit this link for more details: http://mrr.cm/U3T
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and Healthcare Reports at: http://www.marketresearchreports.com/pharma-healthcare
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