CPB is also used in heart valve replacement
and repair procedures, repair of septal and congenital heart defects and transplants.
However, for the purposes of this report, this chapter analyzes the use of CPB
specifically in ONCAB procedures. During an ONCAB procedure, the patient’s
heart is stopped temporarily while surgeons use a continuous thread and hand
sew vessels together to bypass the blockages. During this procedure, a
mechanical cardiopulmonary bypass machine keeps the blood circulating through
the body.
The blood is rerouted through the healthy
vessel and blood flow is restored to the heart muscle. Redirecting the blood
flow to a pump enables the surgeon to clamp the aorta and stop the heart,
resulting in a motionless and bloodless field. This allows the surgeon to
precisely perform manual suturing to obtain accurate connections (anastomoses)
between the graft vessel and the aorta, as well as effectively bypass the
narrowed or obstructed coronary artery. The absence of blood flow and a
motionless heart are important factors in ensuring precision and providing
consistent, reproducible positive clinical outcomes.
There are some downsides to the use of CPB
pumps. Use of the CPB for circulation exposes the patient’s blood to foreign
surfaces, which has been shown to increase the incidence of bleeding and
short-term neurocognitive defects. This is known as post-perfusion syndrome or
“pump head.” Symptoms of post-perfusion syndrome are subtle and include defects
associated with attention, concentration, short-term memory, fine motor
function and speed of mental and motor responses.
Additionally, stopping of the heart may damage
the heart muscle. In certain studies, clamping of the aorta has been shown in
certain studies to cause the release of particles into the blood stream that
may produce blockages in other parts of the body, such as the brain, which may
lead to neurological damage, including strokes. Despite these potential
complications, the majority of CABG procedures are still performed on-pump.
Furthermore, the percentage of total CABG procedures performed on-pump has been
increasing year-over-year since 2004.
The majority of coronary artery bypass
graft (CABG) procedures are performed with the heart stopped. This type of
procedure is termed on-pump coronary artery bypass (ONCAB) because the
procedure requires the usage of a cardiopulmonary bypass (CPB). CPB is a technique
that temporarily takes over the function of the heart and lungs during surgery,
maintaining the circulation of blood and the oxygen content of the body. The
CPB pump itself is often referred to as a heart-lung machine.
In addition to the heart-lung machine, a
complete extracorporeal bypass system is composed of various single-use
products, called disposables for the purposes of this report. As disposables
come into direct contact with the patient’s blood, they cannot be reused for
safety reasons and must be disposed of and replaced following each procedure.
Spanning over 381 pages “US
Market Report for On-Pump Coronary Artery Bypass Devices 2018 - MedCore” report
covers Executive Summary, U.S. Cardiac Surgery And Heart Valve Device Market
Overview, Competitive Analysis, Market Trends, Market Developments, Research
Methodology, Disease Overview, Product Portfolio, On-Pump Coronary Artery
Bypass Device Market, Appendix. This report Covered Companies - Edwards
Lifesciences, St. Jude Medical, Medtronic, Maquet, Abiomed, HeartWare Inc.,
Sorin Group, Terumo, Abbott Laboratories, Teleflex Medical, Cardiac Assist,
AtriCure, W.L. Gore, SynCardia, Boston Scientific, Cryolife, Others include:
Berlin Heart, Cardica, Chase Medical, Genesee Biomedical, Karl Storz, LifeNet
Health, Microline Surgical, Novadaq, On-X, Saphena Medical, SentreHeart,
Vitalitec, etc.
Please visit this link for more details: http://mrr.cm/UG3
Find all Pharma
and Healthcare Reports at: https://www.marketresearchreports.com/pharma-healthcare
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