The vast majority of commercially available
tissue valves are xenograft valves derived from animals. Usually, the valves
are porcine, meaning from a pig, or bovine, meaning from a cow. The porcine
heart is most similar to the human heart and therefore represents the best
anatomical fit for replacement. The tissue of the pericardial sac is
particularly well suited for a valve leaflet due to its extremely durable
physical properties. Before implantation, the tissue undergoes multiple
chemical treatments to make it suitable for replacement in the human heart.
The tissue is sterilized so that the
biological markers are removed, thereby eliminating a response from the host's
immune system. The primary advantage of tissue over mechanical valves is that
tissue valves are much more biocompatible and thus a patient who receives a
tissue valve does not require life-long anti-coagulation therapy. However, a
disadvantage of tissue valves is that they are not as durable and typically
last between 15 and 20 years before requiring replacement.
Nevertheless, advances in polymer coatings
have made tissue valves more durable than ever before. Furthermore, several
aortic tissue valve replacement devices under development that are currently
undergoing clinical trials in the U.S. or awaiting FDA approval may be
implanted percutaneously.
Tissue valves, which are also known as
bioprosthetic valves, are harvested from either human donors or animal tissue.
Human tissue valves can either be obtained from donor cadavers in allograft
procedures, or from one’s own body in an autograft procedure. Allograft valves
may be acquired from deceased family members or anonymous donors.
Autograft valves may be obtained through a
Ross procedure, whereby part of the pulmonary valve is grafted and harvested
into the aortic position. Whether autograft or allograft, human donor valves
involve complicated extraction and insertion procedures. Human tissue valves
are in limited supply and typically do not function drastically better than
xenograft valves.
Spanning over 395 pages “US
Market Report for Tissue Heart Valves 2018 - MedCore” report
covers Executive Summary, U.S. Cardiac Surgery And Heart Valve Device Market
Overview, Competitive Analysis, Market Trends, Market Developments, Research
Methodology, Disease Overview, Product Portfolio, Tissue Heart Valve Market,
Appendix. This report Covered Companies - Edwards Lifesciences, St. Jude
Medical, Medtronic, Maquet, Abiomed, HeartWare Inc., Sorin Group, Terumo,
Abbott Laboratories, Teleflex Medical, Cardiac Assist, AtriCure, W.L. Gore,
SynCardia, Boston Scientific, Cryolife, Others include: Berlin Heart, Cardica,
Chase Medical, Genesee Biomedical, Karl Storz, LifeNet Health, Microline
Surgical, Novadaq, On-X, Saphena Medical, SentreHeart, Vitalitec, etc.
Please visit this link for more details: http://mrr.cm/UGS
Find all Pharma
and Healthcare Reports at: https://www.marketresearchreports.com/pharma-healthcare
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