TCR Engineered T-Cell Therapy 2018: an
industry analysis of technologies, pipelines, stakeholders & deals
T-Cell Receptors (TCR) and Chimeric Antigen
Receptors (CAR) are the cutting edge of adoptive T-cell therapy. Both receptors
deploy T-cells to target the tumor, but CAR T-cells (CAR-T) are limited to
binding to cell surface antigens, while TCR T-cells (TCR-T) recognize peptides
(derived from intracellular proteins) presented on the cell surface by the
major histocompatibility complex (MHC) class I.
TCR-Ts have so far operated in the shadow
of CAR-Ts, but may have the advantage in solid tumors. The first approved
CD19-specific CAR-Ts are indicated for hematologic malignancies, but CAR-Ts
were less successful against solid tumors.
This report „TCR Engineered T-Cell Therapy
2018: an industry analysis of technologies, pipelines, stakeholders &
deals“ published in May 2018 brings you up-to-date regarding key TCR-T players,
key TCR-T technologies and product candidates, business models, deals and
funding opportunities. The report analyzes the TCR-T pipelines and stakeholders
in the field, especially focused and diversified TCR-T companies and their
relationship with academia and major pharma/biotech. The report highlights the
value of TCR-T assets in terms of partnering economic conditions, acquisition
prices and financing rounds.
This report has been prepared by use of
in-house databases and desktop search to identify and describe company,
product, technology and business/financing profiles which then were evaluated
and analyzed with a final outlook describing perspectives with challenges and
opportunities. Sources of information are provided by scientific and
non-scientific references, e.g. press releases, stock exchange disclosures,
presentations, annual reports, fact sheets and patent applications (with
hyperlinks leading to the source of information).
Key
questions answered:
- Which targets are chosen for developmen of TCR-Ts?
- How close are neoantigen-specific TCR-Ts to the clinic?
- Which technologies are used for generation of T-Cell Receptors?
- Has clinical proof-of-concept been shown for any TCR-T?
- How does the TCR-T pipeline look like?
- What manufacturing strategies and solutions have companies chosen?
- Are next generation TCR-Ts already in development?
- What are the key technologies for a successful TCR-T?
- Who are the key players in the TCR-T field?
- How tough is competition among TCR-T developers?
- Should companies be focused on TCR-Ts only or be diversified into various adoptive T-cell therapeutics?
- Which technologies and assets attract licensees?
- How is the financing situation for TCR-T?
- What are the key success factors for TCR-Ts?
Target
audience:
- Leading Pharmaceutical companies
- Suppliers
- Contractors
- Technologists
- R&D staff
- Consultants
- Analyst
- CSO's
- CEO’s
- CIO’s
- COO’s
- Business development managers
- Investors
- Governments
- Agencies
- Industry organisations
- Banks
Spanning over 294 pages “TCR Engineered T-Cell Therapy 2018: an industry
analysis of technologies, pipelines, stakeholders & deals an industry
analysis of technologies, stakeholders, deals & trends” report covers Executive
Summary, Introduction, Overview & Background, Technologies, Pipeline,
Manufacturing, Companies, Business Development & Financing, Outlook &
Perspectives, References. This report Covered 33 Companies few are -
Adaptimmune, Adicet Bio, Aeon Therapeutics Shanghai, AgenTus Therapeutics,
Alpine Immune Science, Atreca, Bellicum Pharmaceuticals, BioNTech, Bluebird
bio, Cell Medica, CRISPR Therapeutics.
Please visit this link for more details: http://mrr.cm/UD5
Find all Pharma
and Healthcare Reports at: https://www.marketresearchreports.com/pharma-healthcare
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