New Drugs to Boost Graft-Versus-Host Disease Treatment Market by 2018, Reveals New Report

The graft-versus-host disease (GVHD) treatment market value will increase from $297 million in 2013 to $407 million by 2018, at a Compound Annual Growth Rate (CAGR) of 6.59%, according to research.

The company’s "OpportunityAnalyzer: Graft-Versus-Host Disease - Opportunity Analysis and Forecasts to 2018" report states that this growth, which will occur over six major markets (6MM: the US, France, Germany, Italy, Spain and the UK), will be strongest in the five European countries (5EU), where multiple product launches will accelerate the market value at a CAGR of 9.26% during the forecast period.

Senior Analyst covering Immunology, says: “Several products are due to enter the GVHD market by 2018, with Osiris Therapeutics and Mesoblast’s first-to-market Prochymal expected to generate sales of $12.2 million in 2018.

According to Analyst, forecast to enter the European GVHD market in 2016, while ATG-Fresenius (ATG-F) will arrive in the US market in 2017. These two products are estimated to achieve 2018 sales of $11,900 and $8 million, respectively.”

The forecasts that both Jazz Pharmaceuticals’ Leukotac and Adienne Pharma’s Begedina will enter the GVHD market in 2018, with Leukotac being launched only in the 5EU. Due to their anticipated premium pricing, these drugs are expected to add over $18 million to the 6MM sales by the end of 2018.

While multiple biologic products will fall off their respective patent cliffs by the end of the forecast period, Vavatsikou states that this will not impact the GVHD forecast for two important reasons.

The analyst explains: “Firstly, biosimilar versions of prominent off-label GVHD biologics, such as Rituxan and Campath/Lemtrada, are in very early development and are yet to succeed in clinical trials.

“Secondly, hematologists across the 6MM are not expected to use biosimilar versions of branded biologics in GVHD patients whose health is already severely compromised.”

Furthermore, key opinion leaders interviewed by GlobalData unanimously agreed that they would prefer new biosimilars to be tested in a GVHD clinical trial setting before they use such treatments in the clinic.

OpportunityAnalyzer: Graft-Versus-Host Disease - Opportunity Analysis and Forecasts to 2018 report provides annualized graft-versus-host disease therapeutics market revenue, cost of therapies and forecasts from 2013 to 2018 across six major markets: the US, France, Germany, Italy, Spain and the UK. Key topics covered include strategic product assessment, market characterization, unmet needs, research and development strategies, clinical trial design, pipeline analysis and competitor evaluations.

Spanning over 252 pages, “OpportunityAnalyzer: Graft-Versus-Host Disease - Opportunity Analysis and Forecasts to 2018” report covering the Disease Overview, Epidemiology, Current Treatment Options, Unmet Need and Opportunity, Research and Development Strategies, Pipeline Assessment, Pipeline and Off-Label Valuation Analysis, Appendix.

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