Patent Expiration of Rilutek to Cause Negative Growth in
Amyotrophic Lateral Sclerosis Treatment Market by 2018.
The amyotrophic lateral sclerosis (ALS) treatment market
value will decline from $64 million in 2013 to $38 million by 2018, at a
negative Compound Annual Growth Rate (CAGR) of 10.05%, according to research
and consulting firm by Publisher.
The company’s latest report states that the largest
factor in this decline, which will occur over seven major markets (7MM: the US,
France, Germany, Italy, Spain, the UK, and Japan), will be the patent
expiration of Rilutek (riluzole), the only approved therapy for ALS.
As a consequence, Publisher forecasts that the ALS
treatment market in the US is set to suffer a substantial reduction in sales
over the forecast period, from $38 million in 2013 to $16 million by 2020, at a
negative CAGR of 16.10%.
Seinor Analyst covering Neurology, says: “The effect of
Rilutek’s patent expiration will be exacerbated by the lack of alternative
treatments in the ALS pipeline. Additionally, the recent failure of several
previously promising Phase III pipeline compounds has restricted the growth of and
interest in the ALS therapeutics market.”
The analyst believes that there is a drastic need for new
therapies that can alleviate the symptoms of the disease and stop or reverse
its pathology. The unmet needs in ALS are reflected in the limited diversity of
the current pipeline, but no dominant theories have emerged to help guide drug
development, according to Nicholson.
“There are two pipeline drugs that will supplement
Rilutek and off-label therapies. AB Science’s AB-1010, an oral tyrosine kinase
inhibitor, targets the inflammatory processes that are believed to contribute
to the pathogenesis of ALS, while Cytokinetics’ tirasemtiv aims to improve
muscle strength through fast-muscle troponin activation. While these
medications will provide greater relief of symptoms, they will not be able to
reverse the course of the disease,” the analyst concludes.
OpportunityAnalyzer:
Amyotrophic Lateral Sclerosis (ALS) - Opportunity Analysis and Forecasts to
2018 report provides an overview
of amyotrophic lateral sclerosis (ALS), including etiology and pathophysiology,
general symptoms, quality of life, country-specific treatment recommendations
and epidemiologic data. It also covers annualized ALS market, treatment and
usage patterns from 2013 to 2018. Key topics covered include unmet needs
analysis, research and development strategies, pipeline assessment and pipeline
valuation analysis.
This report was built using data and information sourced
from proprietary databases, primary and secondary research, and in-house
analysis conducted by Publisher’s team of industry experts.
Spanning over 134 pages, “OpportunityAnalyzer
- Amyotrophic Lateral Sclerosis (ALS) - Opportunity Analysis and Forecasts to
2018” report covering the Disease Overview, Epidemiology,
Current Treatment Options, Unmet Needs Assessment and Opportunity Analysis,
Research and Development Strategies, Pipeline Assessment, Pipeline Valuation
Analysis, Appendix.
Know more about this
report at : http://mrr.cm/ZP3
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