Acute Coronary Syndrome - Global Drug Forecast and Market Analysis to 2023, New Report Launched

New Blockbuster Drugs to More than Triple Acute Coronary Syndrome Treatment Market Value by 2023,

The launch of several drugs with “extraordinary blockbuster potential” will cause the acute coronary syndrome (ACS) treatment market to more than triple in value, from $12.3 billion in 2013 to $43.4 billion by 2023, according to report.

The PharmaPoint: Acute Coronary Syndrome - Global Drug Forecast and Market Analysis to 2023 report states that across seven major markets (the US, France, Germany, Italy, Spain, the UK and Japan) there are three monoclonal antibodies (mAbs), all PCSK9 inhibitors, with the potential to reshape the post-ACS, dyslipidemia landscape.

Amgen’s evolocumab, Sanofi and Regeneron’s alirocumab, and Pfizer’s bococizumab are all demonstrating safe and significant reductions of serum LDL-C levels in major clinical trials, and Publisher expects these treatments to be launched in the middle of the forecast period.

Senior Analyst covering Cardiovascular and Metabolic Disorders, says: “These three mAbs, which fulfill a critical unmet need by offering novel approaches to LDL-C reduction for patients who cannot tolerate statins, are likely to be prescribed long-term, marking the first time that biologics will enter the mainstream of chronic ACS treatment.

The premium price of PCSK9 mAbs means that they will be able to achieve substantial sales with a relatively small patient population. We forecast that they will account for around 40% of ACS sales by 2023, with a global value that slightly exceeds $17.5 billion.

Publisher has also identified two new anticoagulants, Janssen’s Xarelto and Merck’s Zontivity, which are both on track to compete directly with warfarin and post impressive sales over the next nine years.

Senior Analyst say: “Xarelto is anticipated to achieve approval for the ACS indication in the US by 2018. When added to the drug’s mounting sales in the EU, this will result in peak-year sales approaching $8 billion for ACS alone. Meanwhile, the PAR1 inhibitor, Zontivity, which enters the US market in Q3 of 2014, could achieve worldwide sales exceeding $1 billion by 2015.

The dramatic increase in overall ACS market value is attributable to the launch of these and several other drugs currently in the late-stage development pipeline, all of which have extraordinary blockbuster potential,” concludes the analyst.

PharmaPoint: Acute Coronary Syndrome - Global Drug Forecast and Market Analysis to 2023 report provides an overview of Acute Coronary Syndrome (ACS), including epidemiology, etiology, pathophysiology, symptoms, diagnosis and treatment guidelines. The key topics covered include strategic competitor assessment, market characterization, unmet needs, clinical trial mapping, pipeline analysis and implications for the ACS therapeutics market.

Spanning over 471 pages, “PharmaPoint: Acute Coronary Syndrome - Global Drug Forecast and Market Analysis to 2023” report covering the  Introduction, Disease Overview, Epidemiology, Disease Management, Competitive Assessment, Unmet Need and Opportunity, Pipeline Assessment, Market Outlook, Appendix. The report covered companies are - Amgen, AstraZeneca, Bristol-Myers Squibb, Daiichi Sankyo, Eli Lilly, GlaxoSmithKline, Janssen Pharmaceuticals (Johnson & Johnson), The Medicines Company, Merck & Co., Pfizer, Sanofi

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