The contract biomanufacturing global market
is expected to grow at double digit CAGR to reach $36.6 billion by 2025.
Biomanufacturing is a widely used term to
describe manufacture of biologic molecules for various stages of drug
development right from pre-clinical stage to commercial supply. The biologic
drug manufacturing is a complex process involving huge capital and sound
technical expertise. Many large and small pharmaceutical companies are turning
to outsourcing the drug manufacture process to reduce capital investments on
capacities and focus more on their core competencies.
Contract manufacturing organizations,
particularly for R&D and clinical trials, are making product manufacture,
more efficient and often less costly. In addition to that, the use of
single-use bioreactors is effectively reducing the manufacture facility cost.
This option is more viable for smaller and low-funded companies for their
in-house candidate product manufacturing needs, whereby, the companies can
avoid $50-$150 million facility costs for construction of fixed, dedicated
stainless steel bioreactor-based bioprocessing systems and outsource their
manufacturing requirements to CMOs which use single-use facilities which
typically cost $25-$40 million for commercial manufacture.
There is a continued growth of
biopharmaceutical market which is expected to nearly double in next 10 years.
This will be a result of continued new product approvals, expansion of
indications for current products which include less-developed countries
becoming more affluent and increased drug demand of the aging population in the
U.S. and other major pharmaceutical markets. Aging populations are at a high
risk of developing chronic diseases such as cancer and arthritis and these
diseases are being precisely targeted using biopharmaceuticals. Many
blockbuster drugs losing their exclusivity are also giving room for many
biosimilar (and bio-betters) companies to enter into the world’s
biopharmaceuticals market subsequently attracting many CROs, CDMOs, and CMOs to
enter into the picture. Hence, there is every reason to assume that future
growth in biopharmaceutical outsourcing will continue at a minimum X% in
western countries to about X% in Asian countries.
Now-a-days CMOs are gaining much prominence
due to increased demand for the clinical and commercial supply of biologics.
Such prominence is achieved mainly through capacity expansions or more easily
through mergers and acquisitions. In September 2016, Asahi Glass, a Japanese
manufacturer of glass, chemicals, and high-tech materials acquired a leading
European bio-CMO, Biomeva Holding GmbH to expand their life science business
and expand into newer geographies. Contract manufacturing services are mainly
benefitting the small scale companies which lack the facilities for the
biomanufacturing and also intend to not invest in fixed assets like steel
bioreactors and bioprocessing facilities thus giving opportunity for the CMOs
to gain market presence.
The contract biomanufacturing global market
is dominated by North America which contributes to revenue of $XX billion in
2016 growing at a CAGR of X% according to IQ4I estimation. The Asia Pacific
region is witnessing huge growth opportunities in terms of biologics
outsourcing and many local contract manufacturing organizations are taking the
lead in making this region the most sought after destination for biologics
outsourcing. Some of the reasons why countries such as China and India are
favourite destinations for such projects include the lower cost of labour,
higher technical expertise and favourable government regulations in countries
such as China. The Asia Pacific region is valued at $X billion in 2016 and is
expected to grow at a strong X% CAGR from 2016-2025 reaching $X billion by
2025.
The global bio-manufacturing outsourcing
market is driven by factors such as globalization of bio-manufacturing
facilities, increased funding from private venture capitals and government
organizations, increasing outsourcing budgets and emergence of latest
technologies such as single-use bioreactors. Increased funding has been seen as
a boon for Chinese CMOs for becoming a lucrative market for biomanufacturing
outsourcing.
An example of such funding includes Autek
Bio who raised an impressive $100 million for building Asia’s largest CMO
facility in south Beijing from private and government sources. There are
restraints and threats as well which could potentially hamper the biomanufacturing
outsourcing market. These include unequal distribution of biomanufacturing
capacities around the globe which could pose capacity constrains in future,
Stringent regulatory affairs and mandatory cGMP certifications which could make
the drug manufacture process to further low down, outsourcing being restricted
to only small and mid-sized companies are another major restraint where large
companies are looking for CMOs as an option only when there are insufficient
capabilities internally.
Spanning over 206 pages “Contract
Biomanufacturing Services Global Market - Forecast to 2025” report
covers Contract Biomanufacturing Global Market, Market Analysis, Contract
Biomanufacturing Services, Company Profiles. This Report Covered 87 Companies
Few Are - Abzena Plc, Albany Molecular Research, Inc, Asahi Glass Co. Ltd.,
Boehringer Ingelheim, Catalent Inc, Charles River Laboratories, Fujifilm
Diosynth Biotechnologies, Horizon Discovery Group, Plc, Innovent Biologics, Jhl
Biotech Inc., Lonza Group, Merck Kgaa, Patheon N.V., Proteogenix.
Please visit this link for more details: http://mrr.cm/UbZ
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