Human Papillomavirus Protein E7 (E7)
pipeline Target constitutes close to 38 molecules. Out of which approximately
27 molecules are developed by companies and remaining by the
universities/institutes. The latest report Human Papillomavirus Protein E7 (E7)
- Pipeline Review, H2 2017, outlays comprehensive information on the Human
Papillomavirus Protein E7 (E7) targeted therapeutics, complete with analysis by
indications, stage of development, mechanism of action (MoA), route of
administration (RoA) and molecule type.
Human Papillomavirus Protein E7 (E7) -
Human Papilloma Virus (HPV) E7 protein belongs to a group of proteins called
oncoproteins. It plays a role in viral genome replication by driving entry of
quiescent cells into the cell cycle. E7 protein has both transforming and
trans-activating activities. It induces the disassembly of the E2F1
transcription factor from RB1, with subsequent transcriptional activation of
E2F1-regulated S-phase genes. Ii interferes with host histone deacetylation
mediated by HDAC1 and HDAC2, leading to transcription activation. It plays an
important role in the inhibition of both antiviral and antiproliferative
functions of host inteferon alpha. The molecules developed by companies in
Phase III, Phase II, Phase I, Preclinical, Discovery and Unknown stages are 2,
7, 3, 13, 1 and 1 respectively. Similarly, the universities portfolio in Phase
II, Phase I, Preclinical and Discovery stages comprises 3, 1, 6 and 1
molecules, respectively.
Report covers products from therapy areas
Oncology, Women's Health and Infectious Disease which include indications Human
Papillomavirus (HPV) Associated Cancer, Cervical Cancer, Cervical
Intraepithelial Neoplasia (CIN), Head And Neck Cancer Squamous Cell Carcinoma,
Head And Neck Cancer, Anal Cancer, Oropharyngeal Cancer, Hepatocellular
Carcinoma, Human Papillomavirus Infections, Lung Cancer, Metastatic
Transitional (Urothelial) Tract Cancer, Non-Small Cell Lung Carcinoma, Rectal
Cancer and Recurrent Head And Neck Cancer Squamous Cell Carcinoma.
Furthermore, this report also reviews key
players involved in Human Papillomavirus Protein E7 (E7) targeted therapeutics
development with respective active and dormant or discontinued projects. Driven
by data and information sourced from proprietary databases, company/university
websites, clinical trial registries, conferences, SEC filings, investor
presentations and featured press releases from company/university sites and
industry-specific third party sources.
Scope
- The report provides a snapshot of the global therapeutic landscape for Human Papillomavirus Protein E7 (E7)
- The report reviews Human Papillomavirus Protein E7 (E7) targeted therapeutics under development by companies and universities/research institutes based on information derived from company and industry-specific sources
- The report covers pipeline products based on various stages of development ranging from pre-registration till discovery and undisclosed stages
- The report features descriptive drug profiles for the pipeline products which includes, product description, descriptive MoA, R&D brief, licensing and collaboration details & other developmental activities
- The report reviews key players involved in Human Papillomavirus Protein E7 (E7) targeted therapeutics and enlists all their major and minor projects
- The report assesses Human Papillomavirus Protein E7 (E7) targeted therapeutics based on mechanism of action (MoA), route of administration (RoA) and molecule type
- The report summarizes all the dormant and discontinued pipeline projects
- The report reviews latest news and deals related to Human Papillomavirus Protein E7 (E7) targeted therapeutics
Reasons
to buy
- Gain strategically significant competitor information, analysis, and insights to formulate effective R&D strategies
- Identify emerging players with potentially strong product portfolio and create effective counter-strategies to gain competitive advantage
- Identify and understand the targeted therapy areas and indications for Human Papillomavirus Protein E7 (E7)
- Identify the use of drugs for target identification and drug repurposing
- Identify potential new clients or partners in the target demographic
- Develop strategic initiatives by understanding the focus areas of leading companies
- Plan mergers and acquisitions effectively by identifying key players and it’s most promising pipeline therapeutics
- Devise corrective measures for pipeline projects by understanding Human Papillomavirus Protein E7 (E7) development landscape
- Develop and design in-licensing and out-licensing strategies by identifying prospective partners with the most attractive projects to enhance and expand business potential and scope
Spanning over 116 pages “Human
Papillomavirus Protein E7 (E7) - Pipeline Review, H2 2017” report
covers Introduction, Report Coverage, Human Papillomavirus Protein E7 (E7) -
Overview, Human Papillomavirus Protein E7 (E7) - Therapeutics Development,
Human Papillomavirus Protein E7 (E7) - Therapeutics Assessment, Human
Papillomavirus Protein E7 (E7) - Companies Involved in Therapeutics
Development, Human Papillomavirus Protein E7 (E7) - Drug Profiles, Human
Papillomavirus Protein E7 (E7) - Dormant Products, Appendix. This report
Covered Companies - Abion Inc, Advaxis Inc, Bioleaders Corp, BioNTech AG,
Cancer Research Technology Ltd, Etubics Corp, Formune SL, Genexine Inc, Hookipa
Biotech AG, iBio Inc, Immunovaccine Inc, Inovio Pharmaceuticals Inc, MedImmune
LLC, Selecta Biosciences Inc, Transgene SA, VLPbio.
Please visit this link for more details: http://mrr.cm/UqT
Find all Pharma
and Healthcare Reports at: http://www.marketresearchreports.com/pharma-healthcare
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