For a long time, messenger RNA (mRNA) was
thought to be a poor choice for a therapeutic agent given its relatively short
half-life and its immunogenicity. But mRNA is rather versatile and offers a
range of advantages. mRNA lacks genomic integration and its use results in transient
expression of the encoded protein. This favorable safety profile makes mRNA
especially attractive for vaccines and gene editing.
mRNA is well defined chemically which
ensures reproducible manufacturing at high yield, purity and activity. Improvements
of lipid nanoparticle formulations as a vehicle for in vivo systemic delivery
of mRNA has greatly favored the development of in vivo transfection strategies.
mRNA Technologies have attracted more than
US$ 3.4 bln in equity financing and frontloaded partnership payments. Further
billions of US$ have been committed to mRNA R&D funding and potential
milestone payments. A select group of major pharmaceutical and rare disease
specialist biopharmaceutical companies have partnered with mRNA technology companies.
At least 16 mRNA vaccines and therapeutics are in clinical stages and a
considerable number is in IND or pre-IND stage.
This report “mRNA Vaccines &
Therapeutics 2017: an industry analysis of technologies, pipelines,
stakeholders and deals ” as of June 2017 brings you up-to-date regarding key
mRNA players, key mRNA technologies and applications, mRNA vaccines &
therapeutics, business projects, business deals and funding opportunities. The
report analyzes the mRNA vaccine and therapeutic pipelines and stakeholders in
the field, especially technology companies and rare disease biopharma and major
pharmaceutical companies. The report highlights the value of mRNA vaccines and
therapeutics in terms of partnering economic condition and equity financing rounds.
What
will you find in the report?
- Profiles of standardized therapeutic cancer mRNA vaccines
- Profiles of individualized therapeutic cancer mRNA vaccines
- Profiles of therapeutic infectious disease mRNA vaccines
- Profiles of prophylactic infectious disease mRNA vaccines
- Profiles of mRNA protein therapeutics for immuno-oncology
- Profiles mRNA gene editing products
- Profiles of mRNA protein therapeutics for monogenetic rare diseases
- Pipelines of cancer and infectious disease mRNA vaccines
- Pipelines of mRNA Therapeutics for OTC deficiency and cystic fibrosis
- mRNA antibody therapeutics
- Therapeutic mRNA gene editing
- Ex vivo mRNA T-cell engineering
- Profiles of mRNA and delivery technologies
- mRNA technology analysis
- Profiles of mRNA stakeholder companies
- mRNA stakeholder analysis
- mRNA manufacturing
- Financial perspective on mRNA
Spanning over 260 Pages “mRNA
Vaccines & Therapeutics 2017: An Industry Analysis of Technologies,
Pipelines, Stakeholders and Deals” report covers Executive
Summary, Introduction & Overview, Profiles of mRNA-based Vaccines &
Therapeutics, Pipeline Analysis, Profiles of Selected mRNA & Delivery
Technologies, Technology Analysis, Company Profiles, Stakeholder Analysis, mRNA
Manufacturing, Financial Perspective on mRNA, Outlook, References. This report
Covered 37 Companies few are - Acuitas Therapeutics, Alexion Pharmaceuticals,
Arbutus Biopharma, Arcturus Therapeutics, Argos Therapeutics, AstraZeneca,
Bayer, BioNTech, Boehringer Ingelheim, CRISPR Therapeutics, CureVac, eTheRNA
immunotherapies.
Please visit this link for more details: http://mrr.cm/USh
Find all Pharma
and Healthcare Reports at: https://www.marketresearchreports.com/pharma-healthcare
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