Merck's nine-valent pipeline
vaccine V503 offers protection against five additional HPV types not included
in current vaccines. Publisher expects this vaccine to be quickly adopted
following regulatory approval and subsequent recommendations by national
immunization committees. KOLs from across the markets included in this report
expected V503 to be widely used, though it was noted that an inflated price,
relative to current HPV vaccines, could provide some barrier to uptake.
Publisher anticipates that
by 2017, V503 will be the dominant prophylactic HPV vaccine globally and will
realize sales of $1.4 billion in 2022 in the 7MM, Australia, and Canada,
representing a 95% market share. This market share will largely be as a result
of the cannibalization of Merck's existing vaccine Gardasil, of which sales are
expected to decline significantly over the forecast period. The only other
prophylactic HPV vaccine in late-stage clinical development is a low-cost
bivalent vaccine, from Chinese biotechnology company Xiamen Innovax. This
vaccine is primarily being developed as a low-cost vaccine for use in the
domestic market; as such it is unlikely to have an impact upon the markets
included in this report.
Publisher estimates that the
global HPV market generated approximately $1.7 billion in sales in 2012. This
market is expected to experience moderate growth over the next 10 years, with
anticipated sales of over $2.2 billion by 2022. This represents a compound
annual growth rate of 2.6%. HPV vaccine sales in Canada and Australia are
expected to increase at a CAGR of over 9% during the forecast period, driven by
the inclusion of males in routine HPV vaccine recommendations. The US is also
expected to make a significant contribution to market growth, thanks to a large
population and an estimated CAGR of 3%.
Key Findings of Report
- A new nine-valent HPV vaccine is expected to be widely adopted following market approval, stealing market share from existing vaccines. However, a high price represents a potential barrier to market access.
- Significant environmental barriers to HPV vaccination exist, which currently serve to limit vaccine uptake.
- The emphasis of HPV vaccination is shifting away from an initial focus on cervical cancer prevention in females, towards prevention of a range of cancers in both males and females.
- The inclusion of males in routine HPV vaccine recommendations will expand the size of the HPV vaccines market.
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